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SPRAVATO | esketamine

SPRAVATO® (esketamine) is the first and only NMDA receptor antagonist approved for 2 subtypes of MDD in adult patients

Doctor talking about bravado Spravato

SPRAVATO® is a prescription medicine, used along with an antidepressant taken by mouth to treat:

  • Adults with treatment-resistant depression (TRD)

  • Depressive symptoms in adults with major depressive disorder (MDD) with suicidal thoughts or actions

SPRAVATO® is not for use as a medicine to prevent or relieve pain (anesthetic). It is not known if SPRAVATO® is safe or effective as an anesthetic medicine.

It is not known if SPRAVATO® is safe and effective for use in preventing suicide or in reducing suicidal thoughts or actions. SPRAVATO® is not for use in place of hospitalization if your healthcare provider determines that hospitalization is needed, even if improvement is experienced after the first dose of SPRAVATO®.

It is not known if SPRAVATO® is safe and effective in children.

What is Spravato?


SPRAVATO® is indicated, in conjunction with an oral antidepressant, for the treatment of:

  • Treatment-resistant depression (TRD) in adults

  • Depressive symptoms in adults with major depressive disorder (MDD) with acute suicidal ideation or behavior

Limitations Of Use

  • The effectiveness of SPRAVATO in preventing suicide or in reducing suicidal ideation or behavior has not been demonstrated [see Clinical Studies]. Use of SPRAVATO does not preclude the need for hospitalization if clinically warranted, even if patients experience improvement after an initial dose of SPRAVATO.

Spravato Depression Treatment

Healthcare providers may define the term “treatment-resistant depression” differently. In the SPRAVATO® clinical trials, treatment-resistant depression was diagnosed in adults who were struggling with major depressive disorder and had not responded adequately to at least two different antidepressants of adequate dose and duration in the current depressive episode.

What is Treatment resistant depression?

Our Spravato Team

Spravato Tea

Our Spravato team is made up of two highly qualified and experienced healthcare professionals, a Nurse Practitioner (NP) and a Medical Assistant (MA), and other support staff. These individuals bring their unique expertise and skills to the table, providing our patients with the best possible care for their mental health needs. Our NP is a licensed and knowledgeable clinician who is skilled in diagnosing and treating mental health conditions, while the MA provides essential support and assistance to the NP, ensuring patients receive a seamless and personalized care experience. Together, our team of experts works tirelessly to provide the highest quality of care, delivered with compassion and a deep commitment to our patients' well-being.

Spravato Treatment discussion

More About Spravato

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